[Download PDF.l6ZN] Recoding Expansion of Decoding Rules Enriches Gene Expression 24 (Nucleic Acids and Molecular Biology)
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Published on: 2010-03-10
Released on: 2010-03-10
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The literature on recoding is scattered, so this superb book lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modications of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modications of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA. web.mit.edu / jik/src/Attic/kerberos_ password ... 50 1alegna 1hplar 1isg 1st 2 2.22 20 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2060 20b 21 214b 22 22_2 23 24 25 26 27 28 29 2_22 2nd 3 3-Headed 3 ...
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